MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma

首页 > 成果 > 详情

认领

导出

下载 Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhang, Zuping;Tang, Hailin;Wang, Zeyou;Zhang, Baoxin;Liu, Wei;...

通讯作者：

Wu, Minghua

作者机构：

[Wu, Minghua; Tang, Hailin; Zhang, Zuping; Wang, Zeyou; Lu, Hongmei; Li, Xiaoling; Liu, Wei; Xiao, Lan; Wang, Rong; Li, Guiyuan; Liu, Xiaoping] Cent S Univ, Minist Educ, Key Lab Carcinogenesis & Canc Invas, Canc Res Inst, Changsha 410078, Hunan, Peoples R China.

[Zhang, Zuping] Cent S Univ, Dept Parasitol, Changsha 410078, Hunan, Peoples R China.

[Tang, Hailin] Univ S China, Canc Res Inst, Hengyang 421001, Hunan, Peoples R China.

[Zhang, Baoxin] Armed Police Hosp Hunan Prov, Changsha 410008, Hunan, Peoples R China.

[Lu, Hongmei] Cent S Univ, Coll Chem & Chem Engn, Res Ctr Modernizat Chinese Herbal Med, Changsha 410083, Peoples R China.

通讯机构：

[Wu, Minghua] C

Cent S Univ, Minist Educ, Key Lab Carcinogenesis & Canc Invas, Canc Res Inst, 110 Xiang Ya Rd, Changsha 410078, Hunan, Peoples R China.

语种：

英文

关键词：

DNA methylation;MiR-185;Glioma;DNMT1

期刊：

Molecular Cancer

ISSN：

1476-4598

年：

2011

卷：

期：

页码：

1-16

DOI：

10.1186/1476-4598-10-124

基金类别：

111 ProjectMinistry of Education, China - 111 Project [111-2-12]; National Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [30901718, 81171932]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [2010QZZD027]; Hunan Province Natural Sciences Foundations of ChinaNatural Science Foundation of Hunan Province [10JJ3010, 11JJ1013]

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

Background: Perturbation of DNA methylation is frequent in cancers and has emerged as an important mechanism involved in tumorigenesis. To determine how DNA methylation is modified in the genome of primary glioma, we used Methyl-DNA immunoprecipitation (MeDIP) and Nimblegen CpG promoter microarrays to identify differentially DNA methylation sequences between primary glioma and normal brain tissue samples.Methods: MeDIP-chip technology was used to investigate the whole-genome differential methylation patterns in glioma and normal brain tissues. ...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问