[Zhang, Jingjing; Liu, Maojun; Nie, Liangui; Yang, Jun; Wu, Qian; Chen, Jian; Li, Yaling; Yi, Jiali; Zheng, Xia] Univ South China, Affiliated Hosp 1, Dept Cardiol, 69 Chuanshan Rd, Hengyang 421001, Hunan, Peoples R China.

[Chu, Chun] Univ South China, Affiliated Hosp 2, Dept Pharm, 35 Chuanshan Rd, Hengyang 421001, Hunan, Peoples R China.

[Yang, Jun; Chu, Chun] U

Univ South China, Affiliated Hosp 1, Dept Cardiol, 69 Chuanshan Rd, Hengyang 421001, Hunan, Peoples R China.

Univ South China, Affiliated Hosp 2, Dept Pharm, 35 Chuanshan Rd, Hengyang 421001, Hunan, Peoples R China.

beclin 1;collagen;collagen type 1 alpha2;collagen type 3 alpha1;cystathionine gamma lyase;cysteine protease atg4;doxorubicin;gelatinase A;glucose regulated protein 78;growth arrest and DNA damage inducible protein 153;hydrogen sulfide;mammalian target of rapamycin;microtubule associated protein;microtubule associated protein 1a 1b light chain 3;phosphatidylinositol 3 kinase;phosphotransferase;protein disulfide isomerase;protein kinase B;protein kinase RNA like ER kinase;sequestosome 1;tissue inhibitor of metalloproteinase 1;tissue inhibitor of metalloproteinase 2;transforming growth factor beta1;unclassified drug;autophagy related protein;collagen;doxorubicin;hydrogen sulfide;MTOR protein, human;phosphatidylinositol 3 kinase;protein kinase B;target of rapamycin kinase;adult;Akt signaling;animal cell;animal experiment;animal model;animal tissue;Article;autophagy (cellular);cardiac muscle cell;controlled study;endoplasmic reticulum stress;enzyme linked immunosorbent assay;gene expression level;heart;heart muscle fibrosis;histopathology;male;mortality;nonhuman;protein expression level;rat;real time reverse transcription polymerase chain reaction;transmission electron microscopy;Western blotting;animal;autophagy;cardiac muscle;drug effect;fibrosis;gene expression;genetics;metabolism;pathology;signal transduction;Sprague Dawley rat;ultrastructure;Animals;Autophagy;Autophagy-Related Proteins;Collagen;Doxorubicin;Endoplasmic Reticulum Stress;Fibrosis;Gene Expression;Hydrogen Sulfide;Male;Microscopy, Electron, Transmission;Myocardium;Phosphatidylinositol 3-Kinases;Proto-Oncogene Proteins c-akt;Rats, Sprague-Dawley;Signal Transduction;TOR Serine-Threonine Kinases;Transforming Growth Factor beta1

药学与生物科学学院