Betanin, a Natural Product from Red Beets, Improves Endothelial Dysfunction through Activation of Autophagy.

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Li, Junpei;Xu, Luyan;Zha, Duoduo;Zhan, Yixiong;Wu, Yijia;...

作者机构：

[Li, Junpei] Department of Cardiovascular, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, China

[Wu, Yijia; Qian, Yisong; Bai, Xinyan; Xu, Luyan] School of Pharmaceutical Science, Nanchang University, Nanchang, 330006, China

[Wu, Yijia; Chen, Kunhua; Zha, Duoduo; Wang, Linsiqi; Zhan, Yixiong; Qian, Yisong; Mao, Xianxian; Bai, Xinyan; Zuo, Li; Xu, Luyan] Institute of Translational Medicine, Nanchang University, Nanchang, 330031, China

[Wu, Yijia; Chen, Kunhua; Zha, Duoduo; Wang, Linsiqi; Zhan, Yixiong; Qian, Yisong; Mao, Xianxian; Bai, Xinyan; Xu, Luyan] Chongqing Research Institute, Nanchang University, Chongqing, 402660, China

[Luo, Jinghua] Department of Pediatrics, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, China

语种：

英文

关键词：

Betanin;ZO-1autophagy.;adhesion molecule;endothelial dysfunction;inflammation

期刊：

CURRENT MEDICINAL CHEMISTRY

ISSN：

0929-8673

年：

2025

DOI：

10.2174/0109298673244974250507034834

机构署名：

本校为其他机构

摘要：

OBJECTIVE: Endothelial dysfunction is the altered pathological ability of endothelial cells to modulate the passage of cells and solutes across vessels, which underlies the development of inflammatory diseases. Betanin (betanidin-5-O-β-glucoside), a natural product rich in red beets, is a water-soluble nitrogen-containing pigment, and its potential protective effects on cardiovascular disease have been reported. In this study, we investigated the protective role of betanin in vascular endothelial dysfunction induced by TNFα and explored poten...

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Betanin, a Natural Product from Red Beets, Improves Endothelial Dysfunction through Activation of Autophagy.

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