The novel neurite outgrowth inhibitor B (Nogo-B) receptor (NgBR) is specific for Nogo-B, which is highly expressed in various human organs and cells, including the lung, liver, kidney, smooth muscle cells, blood vessel endothelial cells and inflammatory cells. Previous studies have indicated that NgBR directly interacts with Nogo-B and is able to independently influence lipid and cholesterol homeostasis, angiogenesis, N-glycosylation, the epithelialmesenchymal transition, the chemotaxis of endothelial cells and cellular proliferation and apopto...
