National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81170277]; Special Research Fund for the Doctoral Program of Higher Education of China Project [20124324110003]; Aid Program for Science and Technology Innovative Research Team in Higher Educational Institutions of Hunan Province
机构署名：
本校为第一且通讯机构
院系归属：
医学院
摘要：
The aim of the present study was to investigate the attenuation of endothelial cell senescence by H2S and to explore the mechanisms underlying the anti-aging effects of H2S. Senescence was induced in human umbilical vein endothelial cells (HUVECs) by incubation in 25 ?mol/l H2O2 for 1 h. Senescence-associated β-galactosidase (SA-β-gal) activity was examined to determine the effects of H2S on senescent HUVECs. The results indicated that SA-β-gal activity in the H2O2-treated HUVECs was 11.2±1.06%, which was attenuated in the NaHS group. Pretr...
