Objective To investigate the current status and influencing factors of demoralization syndrome in cancer patients. Methods A total of 250 cancer patients were surveyed by utilizing the Chinese version of the Demoralization Scale Ⅱ (DS-Ⅱ) and the Edmonton Symptom Assessment System (ESAS). Results The median (P25 and P75) of demoralization score was 10.0 (7.0, 12.0). The incidence of moderate and severe demoralization syndrome was 47.20% and 4.00% respectively. Multiple linear regression indicated that gender, education level, monthly average i...