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Deep Brain Stimulation in Drug Addiction Treatment: Research Progress and Perspective

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成果类型:
期刊论文
作者:
Chang, Rui;Peng, Jionghong;Chen, Yunfan;Liao, Hailin;Zhao, Size;...
通讯作者:
Tan, S.;Zou, J.
作者机构:
[Tan, Sijie; Chen, Yunfan; Zhao, Size; Chang, Rui; Peng, Jionghong; Liao, Hailin; Zou, Ju] Univ South China, Hengyang Med Coll, Sch Basic Med, Dept Histol & Embryol, Hengyang, Peoples R China.
通讯机构:
[Zou, J.; Tan, S.] D
Department of Histology and Embryology, China
语种:
英文
关键词:
deep brain stimulation;drug addiction;nucleus accumbens;opioids;substantia nigra pars reticulata
期刊:
FRONTIERS IN PSYCHIATRY
ISSN:
1664-0640
年:
2022
卷:
13
页码:
858638
基金类别:
This work was supported by grants from the National Science Foundation of China (NSFC 81301144) and Research Learning and Innovative Experiment Project for University Students of University of South China (210XCX486, 210XCX510, and 200XCX322).
机构署名:
本校为第一机构
院系归属:
医学院
摘要:
Drug addiction is a chronic psychiatric disorder characterized by compulsive drug-seeking and drug-using behavior, and a tremendous socioeconomic burden to society. Current pharmacological and psychosocial methods have shown limited treatment effects for substance abuse. Deep Brain Stimulation (DBS) is a novel treatment for psychiatric disease and has gradually gained popularity in the treatment of addiction. Addiction is characterized by neuroplastic changes in the nucleus accumbens (NAc), a key structure in the brain reward system, and DBS in this region has shown promising treatment effects...

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