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A label-free electrochemical biosensor for trace uranium based on DNAzymes and gold nanoparticles

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成果类型:
期刊论文
作者:
Ma, Dandan;Yuan, Yali*;Xiao, Xilin;Gao, Yangyang;Li, Yuhui;...
通讯作者:
Yuan, Yali
作者机构:
[Gao, Yangyang; Xu, Wenhui; Long, Wei; Xiao, Xilin; Li, Yuhui; Ma, Dandan] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.
[Yuan, Yali] Univ South China, Hengyang, Hunan, Peoples R China.
[Yuan, Yali] Univ South China, 28 Changsheng Rd, Hengyang, Hunan, Peoples R China.
通讯机构:
[Yuan, Yali] U
Univ South China, 28 Changsheng Rd, Hengyang, Hunan, Peoples R China.
语种:
英文
关键词:
Label-free;Electrochemical biosensor;Uranium-special DNAzymes;Gold nanoparticle
期刊:
Journal of Radioanalytical and Nuclear Chemistry
ISSN:
0236-5731
年:
2014
卷:
299
期:
3
页码:
1911-1919
基金类别:
Open Foundation of State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University, China
机构署名:
本校为第一且通讯机构
院系归属:
化学化工学院
摘要:
A novel and highly sensitive electrochemical DNAzymes biosensor was fabricated using Au nanoparticles (AuNPs) immobilized on the surface of Au electrode that had been previously modified with self-assembled monolayers of 1,6-hexanedithiol. Different modified electrodes were prepared and characterized by cyclic voltammetry and electrochemical impedance spectroscopy. The AuNPs were found to have a large surface area to anchor a large number of negatively charged phosphate backbones of DNAzymes, which further absorbed the electroactive indicator o...

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