期刊论文

Yuan, M.-H.

中文

中华实验眼科杂志

2095-0160

2011

29

4

336-340

10.3760/cma.j.issn.2095-0160.2011.04.012

本校为第一且通讯机构

背景去瓣准分子激光角膜上皮瓣下磨镶术(Epi-LASIK)术后上皮愈合快，创伤反应轻，受到眼科医师的关注。但去瓣Epi-LASIK术后上皮愈合的机制一直是目前研究的热点。目的研究兔准分子激光角膜切削术(PRK)和去瓣Epi-LASIK对不同屈光度眼切削术后早期角膜基质中炎性细胞、碱性成纤维细胞生长因子(bFGF)、核转录因子(NF-KB)的表达，探讨两种手术方式在不同切削深度时角膜创伤愈合反应的机制。方法将16只新西兰大白兔按随机数字表法分为高度切削组（-10.00 D）6只、低度切削组（-3.00 D）6只和空白对照组2只。实验组取一侧眼行PRK，对侧眼行去瓣Epi-LASIK，术后每日裂隙灯下观察活体兔角膜愈合情况。术...

Background: Free-flap Epi-LASIK surgery show a fast epithelial healing and mild trauma responses. Its mechanism is notable. Objective: The aim of this study was to compare the corneal epithelial healing response following photorefractive keratectomy (PRK) and flap-free Epi-LASIK surgery. Methods: Twelve experimental rabbits were randomly assigned to high cutting group(-10.00 D) and low cutting group(-3.00D), and 2 normal matched rabbits were used as controls. PRK was performed in lateral eyes and flap-free epipolis laser in situ-keratomileusis(...