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Clinical and Microbiological Characterization of Bloodstream Infections Caused by Mycoplasma hominis: An Overlooked Pathogen

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成果类型:
期刊论文
作者:
Zeng, Tong;Wu, Yuan;Yang, Zhiyu;Luo, Min;Xu, Chang;...
通讯作者:
Zhang, XT;Ouyang, JL;Liu, LG
作者机构:
[Luo, Min; Zeng, Tong; Xu, Chang; Zhang, Xiaotuan; Wu, Yuan; Liu, Zhuoran; Yang, Zhiyu] Univ South China, Affiliated Hosp 3, Hengyang Med Sch, Dept Clin Lab Med, Hengyang 421001, Peoples R China.
[Zhang, Xiaotuan] Wenzhou Med Univ, Affiliated Hosp 1, Dept Clin Lab, Wenzhou 325000, Peoples R China.
[Ouyang, Jinglin] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Ultrasound Med, Hengyang, Peoples R China.
[Liu, LG; Liu, Logen] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Clin Res Ctr, Hengyang 421001, Peoples R China.
通讯机构:
[Liu, LG ; Zhang, XT ; Ouyang, JL ] U
Univ South China, Affiliated Hosp 3, Hengyang Med Sch, Dept Clin Lab Med, Hengyang 421001, Peoples R China.
Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Ultrasound Med, Hengyang, Peoples R China.
Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Clin Res Ctr, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
Mycoplasma hominis;Bloodstream infection;Sepsis;Antibiotic resistance;Quinolone resistance-determining region;China
期刊:
Infectious Diseases and Therapy
ISSN:
2193-8229
年:
2022
卷:
11
期:
3
页码:
1003-1017
基金类别:
The work and Rapid Service Fee were supported by the Natural Science Foundation of Hunan Province (2021JJ40483), Health Commission Program of Hunan province (202211004530 and 202203034469), and the Key Laboratory for Molecular Diagnosis and Precision Medicine in Hengyang (202010041574).
机构署名:
本校为第一且通讯机构
摘要:
Introduction: Bloodstream infection (BSI) is associated with high mortality rates. Mycoplasma hominis, which rarely causes extragenital infections, has been shown to induce BSI and presents a clinical diagnostic and therapeutic challenge. Methods: In this study, we investigated the clinical characteristics, antibiotic resistance, and multilocus sequence typing (MLST) of eight BSI cases caused by M. hominis in South China from January 2018 to October 2021. Results: Underlying immunosuppression and genitourinary tract surgery are important risk f...

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