Nicorandil improves clinical outcomes in patients with stable angina pectoris requiring PCI: a systematic review and meta-analysis of 14 randomized trials

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成果类型：

期刊论文

作者：

Li, Yiliang;Liu, Hai;Peng, Wei;Song, Zhi*

通讯作者：

Song, Zhi

作者机构：

[Li, Yiliang; Song, Zhi] Cent South Univ, Xiangya Hosp 3, Dept Neurol, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China.

[Li, Yiliang] Cent South Univ, Xiangya Hosp 3, Clin Med, Changsha, Hunan, Peoples R China.

[Liu, Hai] Zhengzhou Univ, Affiliated Hosp 1, Dept Cardiac Surg 3, Zhengzhou, Henan, Peoples R China.

[Peng, Wei] Univ South China, Cent Hosp Loudi, Dept Cardiol, Loudi, Peoples R China.

通讯机构：

[Song, Zhi] C

Cent South Univ, Xiangya Hosp 3, Dept Neurol, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China.

语种：

英文

关键词：

Nicorandil;cardiorenal protection;clinical outcomes;elective;percutaneous coronary intervention

期刊：

Expert Review of Clinical Pharmacology

ISSN：

1751-2433

年：

2018

卷：

期：

页码：

855-865

DOI：

10.1080/17512433.2018.1508342

基金类别：

This study was supported by Postdoctoral Science Foundation of Central South University [grant number 182115]; Postdoctoral Science Foundation of Hunan Province [grant number 182115]; National Natural Science Foundation of China [grant number 81500260]; China Postdoctoral Science Foundation [grant number 2018M630916]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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摘要：

Introduction: Clinical trials concerning the effects of nicorandil in stable coronary artery disease (CAD) remain controversial. This study sought to evaluate the clinical outcomes of nicorandil following elective percutaneous coronary intervention (PCI). Areas covered: A meta-analysis including eligible randomized controlled trials (RCTs) with data on the nicorandil in stable CAD from Pubmed, EMBase, and Cochrane library (up to March 2018) was conducted. The primary end points were postprocedural incidence of myocardial infarction (MI) and con...

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Nicorandil improves clinical outcomes in patients with stable angina pectoris requiring PCI: a systematic review and meta-analysis of 14 randomized trials

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