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Melatonin prevents the transgenerational toxicity of nanoplastics in zebrafish (Danio rerio)

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成果类型:
期刊论文
作者:
Zeng, Min;Zhan, Chunhua;Li, Ye;Liao, Hongping;Liu, Wanjing;...
通讯作者:
Wang, J;Chen, Guanglong
作者机构:
[Li, Ye; Zeng, Min; Liao, Hongping; Wang, Jun] South China Agr Univ, Coll Marine Sci, Guangzhou 510642, Peoples R China.
[Wang, Jun] Nansha South China Agr Univ, Fishery Res Inst, Guangzhou 511464, Peoples R China.
[Chen, Guanglong; Wang, Jun] Guangxi Acad Sci, Inst Ecoenvironm Res, Nanning 530007, Peoples R China.
[Liu, Wanjing; Zhan, Chunhua] Univ South China, Sch Publ Hlth, Hunan Prov Key Lab Typ Environm Pollut & Hlth Haza, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Chen, GL] G
[Wang, J ] S
South China Agr Univ, Coll Marine Sci, Guangzhou 510642, Peoples R China.
Nansha South China Agr Univ, Fishery Res Inst, Guangzhou 511464, Peoples R China.
Guangxi Acad Sci, Inst Ecoenvironm Res, Nanning 530007, Peoples R China.
语种:
英文
关键词:
Larvae;Melatonin;Polystyrene nanoplastics;Transgenerational toxicity;Zebrafish
期刊:
Science of The Total Environment
ISSN:
0048-9697
年:
2024
卷:
953
页码:
176043
基金类别:
CRediT authorship contribution statement Min Zeng: Writing – original draft, Methodology, Formal analysis, Data curation, Conceptualization. Chunhua Zhan: Writing – review & editing, Supervision, Conceptualization. Ye Li: Investigation. Hongping Liao: Investigation. Wanjing Liu: Investigation. Guanglong Chen: Methodology, acquisition. Jun Wang: Methodology, acquisition, Formal analysis, Conceptualization.
机构署名:
本校为其他机构
院系归属:
公共卫生学院
摘要:
As a novel pollutant, microplastic pollution has become a global environmental concern. Melatonin (MT) has a protective effect on the damage caused by pollutants. However, there is still a lack of research on the transgenerational toxicity of microplastics and the alleviation of microplastics toxicity by MT. In this study, the adult zebrafish was exposed to (0, 0.1 and 1mg/L) polystyrene nanoplastics (PSNP) with or without (1μM) MT for 14days, and embryos (F1) were used for experiments. Our study found that long-term exposure of parents to 1mg...

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