期刊论文

Qu, Shun-Lin

英文

Clinica Chimica Acta

0009-8981

2015

438

112-118

10.1016/j.cca.2014.08.005

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81100212, 81170277, 81100106]; Ph.D. Programs Foundation of the Ministry of Education of the People's Republic of China [20114324120004, 20124324110003]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2012M511383]; Scientific Research Fund of Hunan Provincial Education DepartmentHunan Provincial Education Department [11C1094, 11C1095]; Science and Technology Project of Hunan Province [2014FJ3014]; Aid Program for Science and Technology Innovative Research Team in Higher Educational Institutions of Hunan Province [2008-244]; Construct Program of the Key Discipline in Hunan Province [2011-76]

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For more than a century, hydrogen sulfide (H2S) has been regarded as a toxic gas. Recently, the understanding of the biological effects of H2S has been changed. This review surveys the growing recognition of H2S as an endogenous signaling molecule in mammals, with emphasis on its physiological and pathological pathways in the urinary system. This article reviews recent progress of basic and pharmacological researches related to endogenous H2S in urinary system, including the regulatory effects of H2S in the process of antioxidant, inflammation,...