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Causes and predictors of mortality from lupus nephritis in Southern Hunan, China

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成果类型:
期刊论文
作者:
Liu, Peng;Peng, Zhong;Xiang, Yazhou;Duan, Yingjie;Huang, Hong;...
通讯作者:
He, Zhangxiu
作者机构:
[Ou, Jihong; Duan, Yingjie; Yang, Bo; Liu, Peng; Xiang, Yazhou; Peng, Zhong; He, Zhangxiu] Univ South China, Affiliated Hosp 1, Dept Nephrol, 69 Chuanshan Rd, Hengyang 421000, Hunan, Peoples R China.
[Peng, Zhong] Univ South China, Affiliated Hosp 1, Dept Gastroenterol, Hengyang, Hunan, Peoples R China.
[Huang, Hong] Univ South China, Affiliated Hosp 1, Inst Clin Med, Hengyang, Hunan, Peoples R China.
[Peng, Zhiyong] Univ South China, Affiliated Hosp 2, Dept Cardiol, Hengyang, Hunan, Peoples R China.
[Zhang, Yong] Hua Yuan Cty Peoples Hosp, Tujia Miao Autonomous Prefecture Xiangxi, Dept Nephrol, Xiangxi, Hunan, Peoples R China.
通讯机构:
[He, Zhangxiu] U
Univ South China, Affiliated Hosp 1, Dept Nephrol, 69 Chuanshan Rd, Hengyang 421000, Hunan, Peoples R China.
语种:
英文
关键词:
Lupus nephritis;mortality;outcome;platelet-to-neutrophil ratio
期刊:
Modern Rheumatology
ISSN:
1439-7595
年:
2022
卷:
32
期:
2
页码:
338-344
基金类别:
The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was in part supported by the National Natural Science Foundation of China [81900678], Scientific Research Project of Hunan Health Committee [202103051523], and Clinical Research Project of University of South China [USCKF201902G03].
机构署名:
本校为第一且通讯机构
院系归属:
医学院
摘要:
Abstract Objectives The objective of the study was to explore the causes and predictors of mortality in a cohort of LN with LN in southern Hunan, China. Methods We analyzed 236 patients with biopsy-proven LN during 2010–2018. Demographic data, laboratory data, SLEDAI scores, treatment strategies, and comorbidity were collected. Cox regression analysis was carried out to determine the independent predictors of mortality. Results The patients had mean disease duration of 67.9 ± 28.2 months. Class IV LN was the predominant biop...

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