The lipid metabolism remodeling: A hurdle in breast cancer therapy

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Xiao, Qian;Xia, Min;Tang, Weijian;Zhao, Hu;Chen, Yajun;...

通讯作者：

Zhong, J;Chen, YJ

作者机构：

[Zhong, Jing; Zhao, Hu; Zhong, J; Xia, Min; Xiao, Qian] Univ South China, Affiliated Hosp 1, Canc Res Inst, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

[Xiao, Qian] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Clin Lab Med, Hengyang 421001, Hunan, Peoples R China.

[Tang, Weijian] Nanchang Univ, Queen Mary Sch, Nanchang 330031, Peoples R China.

[Chen, Yajun] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Metab & Endocrinol, Hengyang 421001, Hunan, Peoples R China.

[Zhong, Jing] Univ South China, Affiliated Hosp 1, Inst Clin Med, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Chen, YJ ; Zhong, J ] U

Univ South China, Affiliated Hosp 1, Canc Res Inst, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Metab & Endocrinol, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

Breast cancer;Lipid metabolism;Targeting therapy;Therapy resistance

期刊：

Cancer Letters

ISSN：

0304-3835

年：

2024

卷：

582

页码：

216512

DOI：

10.1016/j.canlet.2023.216512

基金类别：

CRediT authorship contribution statement Qian Xiao: Writing – original draft, Conceptualization. Min Xia: Writing – review & editing. Weijian Tang: Writing – review & editing. Hu Zhao: Writing – review & editing. Yajun Chen: Writing – review & editing. Jing Zhong: Writing – review & editing, acquisition, Conceptualization.

机构署名：

本校为第一且通讯机构

院系归属：

医学院

摘要：

Lipids, as one of the three primary energy sources, provide energy for all cellular life activities. Lipids are also known to be involved in the formation of cell membranes and play an important role as signaling molecules in the intracellular and microenvironment. Tumor cells actively or passively remodel lipid metabolism, using the function of lipids in various important cellular life activities to evade therapeutic attack. Breast cancer has become the leading cause of cancer-related deaths in women, which is partly due to therapeutic resistance. It is necessary to fully elucidate the format...

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The lipid metabolism remodeling: A hurdle in breast cancer therapy

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