期刊论文

英文

AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH

1943-8141

2022

14

10

7239-7251

Self-funded Scientific Research Project of Western Medicine of the Health Committee of Guangxi Autonomous Region [Z20210083]; Guangxi Natural Science Foundation Project [2018GXNSFAA281122]; Medical and Health Development and Application Project of Guangxi Zhuang Autonomous Region [S2017010]; NSFC cultivation project of The Second affiliated hospital of Guangxi Medical University [GJPY2018009]

本校为其他机构

Microscopic polyangiitis (MPA) is a type of antineutrophil cytoplasmic antibody (ANCA)-related vasculitis. Autophagy-related gene 7 (ATG7) protects against complicated disorder states in model organisms, but the way ATG7 dysfunction contributes to MPA remains elusive. This investigation assessed the impacts of ATG7 singlenucleotide polymorphisms (SNPs) on microscopic polyangiitis (MPA) in China. A total of 211 controls and 214 MPA patients were recruited and analyzed. Polymerase chain reaction (PCR) and high-throughput sequencing were adopted to detect the ATG7 SNPs (rs75492008, rs2594966, rs6...