The interactions and biological pathways among metabolomics products of patients with coronary heart disease

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成果类型：

期刊论文

作者：

Chu, Chun;Liu, Shengquan;Nie, Liangui;Hu, Hongming;Liu, Yi;...

通讯作者：

Yi Liu<&wdkj&>Jun Yang

作者机构：

[Chu, Chun] Department of Pharmacy, The Second Affiliated Hospital, Hengyang Medical School, University of South China,Hengyang,Hunan Province 421001,China

[Nie, Liangui; Hu, Hongming; Liu, Shengquan] Department of Cardiology, The First Affiliated Hospital, Hengyang Medical School, University of South China,Hengyang,Hunan Province 421001,China

[Liu, Yi] Department of Pharmacy, The Second Affiliated Hospital, Hengyang Medical School, University of South China,Hengyang,Hunan Province 421001,China. Electronic address: xiziju48262422@163.com

[Yang, Jun] Department of Cardiology, The First Affiliated Hospital, Hengyang Medical School, University of South China,Hengyang,Hunan Province 421001,China. Electronic address: weidongyang@mailfence.com

通讯机构：

[Yi Liu; Jun Yang] D

Department of Cardiology, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan Province 421001, China<&wdkj&>Department of Pharmacy, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan Province 421001, China

语种：

英文

关键词：

Bioinformatics;Biological pathway analysis;Coronary heart disease;Metabolites interaction;Metabolomics

期刊：

Biomedicine & Pharmacotherapy

ISSN：

0753-3322

年：

2024

卷：

173

页码：

116305

DOI：

10.1016/j.biopha.2024.116305

基金类别：

The research is supported by: This project was supported by the National Natural Science Foundation of China (No. 82074236), Clinical Major Projects of Hunan Provincial Health Commission (No. 20201913), the Natural Science Foundation of Hunan Province (No. 2021JJ70035).

机构署名：

本校为第一且通讯机构

院系归属：

药学与生物科学学院

摘要：

BACKGROUND: Through bioinformatics analysis, this study explores the interactions and biological pathways involving metabolomic products in patients diagnosed with coronary heart disease (CHD). METHODS: A comprehensive search for relevant studies focusing on metabolomics analysis in CHD patients was conducted across databases including CNKI, Wanfang, VIP, CBM, PubMed, Cochrane Library, Nature, Web of Science, Springer, and Science Direct. Metabolites reported in the literature underwent statistical analysis and summarization, with the identification of differential metabolites. The pathways as...

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The interactions and biological pathways among metabolomics products of patients with coronary heart disease

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