期刊论文

Liu, J.;Zhao, H.

英文

FRONTIERS IN HUMAN NEUROSCIENCE

1662-5161

2022

15

755017

10.3389/fnhum.2021.755017

This work was supported by Hunan Provincial Science and Technology Innovation Program of China [Grant No. 2017SK50203 (HZ)], Scientific Research Fund Project of Hunan Provincial Health Commission [Grant No. 20201911 (HZ)], Science and Technology Project of Hengyang [Grant No. HCJZ20206720 (JCL)], Hunan Provincial Natural Science Foundation of China [Grant No. 2018JJ2357 (GHL)], and Hunan Provincial Innovation Foundation for Postgraduate [Grant No. CX203YSC066 (TQY)].

本校为第一机构

Type 2 diabetes mellitus (T2DM) is associated with cognitive impairment in many domains. There are several pieces of evidence that changes in neuronal neuropathies and metabolism have been observed in T2DM. Structural and functional MRI shows that abnormal connections and synchronization occur in T2DM brain circuits and related networks. Neuroplasticity and energy metabolism appear to be principal effector systems, which may be related to amyloid beta (Aβ) deposition, although there is no unified explanation that includes the complex etiology ...