Role of endothelial-mesenchymal transition in the tumorigenesis of infantile hemangioma

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成果类型：

期刊论文

作者：

Yang, Wen-Ping;Zhang, Yu;Su, Yue;Cao, Zao-Hui;He, Jia-Shu;...

通讯作者：

Deng, Huan

作者机构：

[Yang, Wen-Ping; Huang, Hui] Jiangxi Childrens Hosp, Dept Pathol, Nanchang, Jiangxi, Peoples R China.

[Xu, Wei] Jiangxi Childrens Hosp, Dept Genl Surg, Nanchang, Jiangxi, Peoples R China.

[Tong, Fei; Li, Zhen; Zhang, Si-Yao; Zhang, Yu; Chen, Yuan; Su, Yue; He, Jia-Shu] Nanchang Univ, Med Coll, Nanchang, Jiangxi, Peoples R China.

[Zhang, Yu; Wang, Meng-Meng; Hu, Jin-Ping; Zhou, Lv; Deng, Yan-Juan; Deng, Huan; Su, Yue] Nanchang Univ, Dept Pathol, Affiliated Hosp 4, Nanchang, Jiangxi, Peoples R China.

[Zhang, Yu; Sun, Jian; Wang, Meng-Meng; Deng, Huan; Lou, Xiao-Liang; Chen, Nan-Ping; Su, Yue] Nanchang Univ, Affiliated Hosp 4, Mol Med & Genet Ctr, Nanchang, Jiangxi, Peoples R China.

通讯机构：

[Deng, Huan] N

Nanchang Univ, Dept Pathol, Affiliated Hosp 4, Nanchang, Jiangxi, Peoples R China.

语种：

英文

关键词：

Endothelial-mesenchymal transition;infantile hemangioma;immunohistochemistry;tumorigenesis;proliferation

期刊：

International Journal of Clinical and Experimental Pathology

ISSN：

1936-2625

年：

2017

卷：

期：

页码：

6751-6758

基金类别：

This study was supported by grants from the National Natural Science Foundation of China (No. 81300347, 81302079), the Natural Science Foundation of Jiangxi Province, China (No. 20151BAB215008, 20151BBG70200), and Foundation of Health and Family Planning Commission of Jiangxi Province (No. 20155592, 20155103, 20161086, 20161093, 201710-98), and Nature Science Fund of Hunan Province (2016jj2113), and Science Fund of Hunan Provincial Education Department (16A186).

机构署名：

本校为其他机构

院系归属：

药学与生物科学学院

摘要：

The aim of this study was to investigate the relationship between endothelial-mesenchymal transition (EndoMT) and the progression of infantile hemangioma (IH) and to provide references for clinical. Sixty-five patients were enrolled in this study. Tissues obtained from these patients were analyzed by tissue microarray (TMA). Serial sections from TMA blocks underwent immunohistochemistry with the primary antibodies for EndoMT markers (Twist, Zeb1, Smad, N-cadherin, Vimentin, and α-SMA). Intensity and extent points were counted to quantitate the...

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Role of endothelial-mesenchymal transition in the tumorigenesis of infantile hemangioma

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