DUSP6: Potential interactions with FXR1P in the nervous system

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成果类型：

期刊论文

作者：

Ma, Yun*;Liu, Yixuan;He, Shuya;Jiang, Zhisheng

通讯作者：

Ma, Yun;He, SY;Ma, Y

作者机构：

[He, Shuya; Liu, Yixuan; Ma, Yun; He, SY] Univ South China, Hengyang Med Sch, Inst Biochem & Mol Biol, Hengyang 421001, Peoples R China.

[Liu, Yixuan; Jiang, Zhisheng; Ma, Yun] Univ South China, Hengyang Med Sch, Inst Cardiovasc Dis, Key Lab Arteriosclerol Hunan Prov,Hunan Int Sci &, Hengyang 421001, Peoples R China.

[Ma, Yun] Univ South China, Hengyang Med Sch, Key Lab Ecol Environm & Crit Human Dis Prevent, Hunan Prov Dept Educ, Hengyang 421001, Peoples R China.

[Ma, Yun] Univ South China, Hengyang Med Sch, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang 421001, Peoples R China.

通讯机构：

[Ma, Y; He, SY ; Ma, Y ] U

Univ South China, Hengyang Med Sch, Inst Biochem & Mol Biol, Hengyang 421001, Peoples R China.

Univ South China, Hengyang Med Sch, Inst Cardiovasc Dis, Key Lab Arteriosclerol Hunan Prov,Hunan Int Sci &, Hengyang 421001, Peoples R China.

Univ South China, Hengyang Med Sch, Key Lab Ecol Environm & Crit Human Dis Prevent, Hunan Prov Dept Educ, Hengyang 421001, Peoples R China.

Univ South China, Hengyang Med Sch, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang 421001, Peoples R China.

语种：

英文

关键词：

Apoptosis;Co-localization;ERK1/2;Nervous system;SK-N-SH

期刊：

INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS

ISSN：

0301-1208

年：

2022

卷：

期：

页码：

229-237

机构署名：

本校为第一且通讯机构

院系归属：

医学院

药学与生物科学学院

摘要：

Fragile X syndrome (FXS) is a leading genetic cause of autism intellectual disorder and autism spectrum disorder (ASD), with either limited treatment options or incurable. Fragile X-related gene 1 (FXR1) is a homolog of the Fragile X mental retardation gene 1 (FMR1), the causative gene of FXS, and both are highly homologous and functionally identical. In FXS, both PI3K (AKT/mTOR signaling pathway) and ERK1/2 (MAPK signaling pathway) expression levels were abnormal. Dual specificity phosphatase 6 (DUSP6) is a member of the mitogen-activated prot...

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DUSP6: Potential interactions with FXR1P in the nervous system

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