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Antitumor activity of Polygonatum sibiricum polysaccharides

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成果类型:
期刊论文
作者:
Lai, Weiwei;Ning, Qian;Wang, Guihua;Gao, Yuan;Liao, Shuxian;...
通讯作者:
Tang, SS
作者机构:
[Lai, Weiwei; Wang, Guihua; Tang, SS; Tang, Shengsong; Liao, Shuxian] Univ South China, Hunan Prov Key Lab Tumor Microenvironm Respons Dru, Hengyang 421001, Peoples R China.
[Lai, Weiwei; Wang, Guihua; Tang, SS; Tang, Shengsong; Liao, Shuxian] Univ South China, Inst Pharm & Pharmacol, Hengyang 421001, Peoples R China.
[Gao, Yuan; Lai, Weiwei; Wang, Guihua; Tang, SS; Tang, Shengsong; Liao, Shuxian; Ning, Qian] Hunan Univ Med, Sch Pharmaceut Sci, Hunan Prov Key Lab Antibody Based Drug & Intellige, Huaihua 418000, Peoples R China.
[Tang, SS; Tang, Shengsong; Ning, Qian] Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha 410128, Peoples R China.
通讯机构:
[Tang, SS ] U
Univ South China, Hunan Prov Key Lab Tumor Microenvironm Respons Dru, Hengyang 421001, Peoples R China.
Univ South China, Inst Pharm & Pharmacol, Hengyang 421001, Peoples R China.
Hunan Univ Med, Sch Pharmaceut Sci, Hunan Prov Key Lab Antibody Based Drug & Intellige, Huaihua 418000, Peoples R China.
Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha 410128, Peoples R China.
语种:
英文
关键词:
Polygonatum sibiricum polysaccharide (PSP);Antitumor;Immunomodulation;Mechanism;Extraction
期刊:
Archives of Pharmacal Research
ISSN:
0253-6269
年:
2024
卷:
47
期:
8
页码:
696-708
基金类别:
Hunan Provincial Science and Technology Plan Key Projects of China; Natural Science Foundation of Hunan Province of China [2024JJ7324]; Scientific Research Fund of Hunan Provincial Education Department [23B1042]; Scientific Research Project of Hunan Provincial Health Commission [202113022028]; [2017SK2183]
机构署名:
本校为第一且通讯机构
院系归属:
药学与生物科学学院
摘要:
Cancer is a global public health problem. Natural polysaccharides have been shown to enhance the effectiveness of cancer treatments. Polygonatum sibiricum (PS) has been used for millennia to treat diverse diseases. PS comprises numerous active constituents, including saponins, peptides, volatile oils, polysaccharides, and lectins. Many studies have highlighted the crucial role of polysaccharides in PS. Modern studies have shown that Polygonatum sibiricum polysaccharide (PSP) exhibits diverse pharmacological activities, including immunomodulatory, antitumor, antioxidant, and anti-aging effects....

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