Long Noncoding RNA OIP5-AS1 Promotes the Disease Progression in Nasopharyngeal Carcinoma by Targeting miR-203

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Tang, Jian;Fu, Chengxiao;Li, Yanwen;Chen, Shuangqin;Jiang, Xiaoxin;...

通讯作者：

Xie, Haitao

作者机构：

[Tang, Jian] Univ South China, Affiliated Hosp 1, Dept Infect Dis, Hengyang 421001, Peoples R China.

[Fu, Chengxiao] Univ South China, Affiliated Hosp 1, Dept Pharm, Hengyang 421001, Peoples R China.

[Xu, Wenqian; Xie, Haitao; Li, Yanwen; Jiang, Xiaoxin] Univ South China, Affiliated Hosp 1, Dept Lab Med, Hengyang 421001, Peoples R China.

[Chen, Shuangqin] Univ South China, Affiliated Hosp 1, Dept Neurol, Hengyang 421001, Peoples R China.

通讯机构：

[Xie, Haitao] U

Univ South China, Affiliated Hosp 1, Dept Lab Med, Hengyang 421001, Peoples R China.

语种：

英文

期刊：

BioMed Research International

ISSN：

2314-6133

年：

2021

卷：

2021

页码：

1-13

DOI：

10.1155/2021/9850928

基金类别：

Natural Scientific Foundation of Hunan Province [2019JJ80035]

机构署名：

本校为第一且通讯机构

院系归属：

医学院

药学与生物科学学院

摘要：

Nasopharyngeal carcinoma (NPC) is a kind of malignancy generated from the nasopharyngeal epithelium. Recently, long noncoding RNA (lncRNA) has been shown to be involved in the regulation of many signaling pathways and is closely associated with carcinogenesis and tumor progression. However, the precise role of lncRNA Opa-interacting protein 5 antisense RNA 1 (OIP5-AS1) in NPC is not well understood. Here, we find that OIP5-AS1 is overexpressed in NPC patient specimens and NPC cell lines. Further investigations reveal that knockdown of OIP5-AS1 ...

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Long Noncoding RNA OIP5-AS1 Promotes the Disease Progression in Nasopharyngeal Carcinoma by Targeting miR-203

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