Objective To investigate the feasibility of proliferating cell nuclear antigen (PCNA) as an sensitive maker of neoadjuvant chemotherapy in patients with locally advanced cervical cancer.Methods Data of 49 patients with locally advanced cervical cancer who received neoadjuvant chemotherapy in the First Affiliated Hospital of Nanhua University from January 2007 to September 2007 were analyzed retrospectively. Expression of PCNA in cervical tissues before and after neoadjuvant chemotherapy were examined by immunohistochemical staining. The clini...