Synthesis and Anti-cancer Activities of Fluorinated Apigenin Derivatives

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成果类型：

会议论文

作者：

Xu Yao,;Zehua Yang,;Zhuo Liu,;Jin Long,;Menghui Xiang,;...

作者机构：

[Xu Yao,; Zehua Yang,; Zhuo Liu,; Jin Long,; Menghui Xiang,; Yi Gao,,; Baojun Su,,; Ye Zhang,,; Hong Li,,; Siyu Wu,,; Tingjuan Wu,,; Xing Zheng,] Institute of Pharmacy & Pharmacology, University of South China

[Xu Yao,; Zehua Yang,; Zhuo Liu,; Jin Long,; Menghui Xiang,; Yi Gao,,; Baojun Su,,; Ye Zhang,,; Hong Li,,; Siyu Wu,,; Tingjuan Wu,,; Xing Zheng,] Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study

[Xu Yao,; Zehua Yang,; Zhuo Liu,; Jin Long,; Menghui Xiang,; Yi Gao,,; Baojun Su,,; Ye Zhang,,; Hong Li,,; Siyu Wu,,; Tingjuan Wu,,; Xing Zheng,] Research Interest Group, University of South China

语种：

中文

关键词：

Anti-cancer activities;Fluorinated apigenin;5-Fu;SAR

年：

2016

页码：

会议名称：

中国化学会第十四届全国氟化学会议

会议论文集名称：

中国化学会第十四届全国氟化学会议论文集

会议时间：

2016-11-18

会议地点：

中国福建福州

基金类别：

Supported by the National Natural Science Foundation of China(No.81273537);the Key Project of Ministry of Education of the People’s Republic of China;the College Students’ Innovative Projects of Hunan Province;the Zhengxiang Scholar Program of the University of South China

机构署名：

本校为第一机构

院系归属：

药学与生物科学学院

摘要：

A novel series of fluorinated apigenin derivatives were synthesized and in vitro inhibitory activities against HL-60,HT-29 and SGC-7901 tumor cell lines were evaluated by the standard methyl thiazole tetrazolium（MTT） method. The results showed that some of fluorinated apgenin derivatives had...

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Synthesis and Anti-cancer Activities of Fluorinated Apigenin Derivatives

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