National Nature Science Foundation of China [11904161, 12274200]; Hengyang science and technology [202250045335]
机构署名：
本校为第一机构
院系归属：
数理学院
摘要：
A large necrotic core increases the risk of atherosclerotic plaque instability. Statins can delay the growth of necrotic core in plaques, but the kinetic mechanism of statins in slowing down the necrotic core has not yet been addressed in detail. In this paper, a mathematical model is governed by a system of advection-diffusion-reaction equations coupling of the porous nature of vessel wall is established and applied to illustrate the plaque growth with lipid-rich necrotic core (LRNC) with and without statins using finite element method. We study the influence of LRNC plaque growth for differe...
