In vitro measurement of superoxide dismutase-like nanozyme activity: a comparative study

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成果类型：

期刊论文

作者：

Liu, Yufeng;Zhang, Yihong;Liu, Quanyi;Wang, Quan;Lin, Anqi;...

通讯作者：

Wei, Hui

作者机构：

[Liu, Yufeng; Wei, Hui; Lin, Anqi; Zhang, Yihong; Wang, Quan] Nanjing Univ, Coll Engn & Appl Sci, Dept Biomed Engn, Nanjing 210023, Jiangsu, Peoples R China.

[Liu, Quanyi; Du, Yan] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Jilin, Peoples R China.

[Luo, Jie; Lin, Ying-Wu] Univ South China, Lab Prot Struct & Anct, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.

[Wei, Hui] Nanjing Univ, Nanjing Natl Lab Microstruct, Jiangsu Key Lab Artificial Funct Mat, Nanjing 210093, Jiangsu, Peoples R China.

[Wei, Hui] Nanjing Univ, State Key Lab Analyt Chem Life Sci, Sch Chem & Chem Engn, Chem & Biomed Innovat Ctr ChemBIC, Nanjing 210023, Jiangsu, Peoples R China.

通讯机构：

[Wei, Hui] N

Nanjing Univ, Coll Engn & Appl Sci, Dept Biomed Engn, Nanjing 210023, Jiangsu, Peoples R China.

Nanjing Univ, Nanjing Natl Lab Microstruct, Jiangsu Key Lab Artificial Funct Mat, Nanjing 210093, Jiangsu, Peoples R China.

Nanjing Univ, State Key Lab Analyt Chem Life Sci, Sch Chem & Chem Engn, Chem & Biomed Innovat Ctr ChemBIC, Nanjing 210023, Jiangsu, Peoples R China.

语种：

英文

关键词：

measurement;superoxide;dismutase-like

期刊：

ANALYST

ISSN：

0003-2654

年：

2021

卷：

146

期：

页码：

1872-1879

DOI：

10.1039/d0an02164d

基金类别：

National Key R&D Program of China [2019YFA0709200]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21722503, 21874067]; PAPD Program; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [021314380145, 021414380485]

机构署名：

本校为其他机构

院系归属：

化学化工学院

摘要：

Analyzing the SOD-like activity of nanozymes in vitro is of great importance for identifying new nanozymes and predicting their potential biological effects in vivo. However, false negative or positive results occasionally occur due to the mismatch between the detection methods and nanozymes. Here, five typical SOD-like nanozymes, including CeO2, Mn3O4, Prussian blue (PB), PCN222-Mn, and Pt NPs, have been used to evaluate the sensitivity and accuracy of several commonly used in vitro detection methods. By systematically analyzing the detection ...

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In vitro measurement of superoxide dismutase-like nanozyme activity: a comparative study

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