期刊论文

Zeng, Q

英文

Gene

0378-1119

2023

876

147514

10.1016/j.gene.2023.147514

This work was supported by Excellent Youth Project of Hunan Provincial Education Department [Grant No. 22B0411 ]; the Natural Science Foundation of Hunan Province [Grant No. 2020JJ5479 ]; Hunan Provincial Department of Education Project [Grant No. 19C1604 ]; Hunan Provincial Innovation Foundation for Postgraduate [Grant No. CX20210960 ].

本校为第一且通讯机构

Background: LIM domain is considered to be important in mediating protein–protein interactions, and members of the LIM protein family can co-regulate tissue-specific gene expression by interacting with different transcription factors. However, its exact function in vivo remains unclear. Our study demonstrates that the LIM protein family member Lmpt may act as a cofactor that interacts with other transcription factors to regulate cellular functions. Methods: In this study, we generated Lmpt knockdown Drosophila (Lmpt-KD) using the UAS-Gal4 syst...