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Molecular design strategy for microorganism discrimination based on keto-salicylaldehyde azine derivatives

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成果类型:
期刊论文
作者:
Yan, Caihong;Zhang, Kexin;Zeng, Yuhang;Deng, Qiyun;Zhou, Fan;...
通讯作者:
Hu, R;Wang, ZM
作者机构:
[Zeng, Yuhang; Hu, R; Yan, Caihong; Hu, Rong; Li, Jiayi] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
[Deng, Qiyun; Zhang, Kexin; Wang, Zhiming; Zhou, Fan; Wang, ZM] South China Univ Technol, AIE Inst, Ctr Aggregat Induced Emiss, State Key Lab Luminescent Materials & Devices,Guan, Guangzhou 510640, Peoples R China.
[Yan, Caihong] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.
[Tang, Ben Zhong] Chinese Univ Hong Kong, Sch Sci & Engn, Shenzhen 518172, Guangdong, Peoples R China.
[Tian, Ying; Gao, Hanyi] Univ South China, Affiliated Hosp 7, Hunan Prov Vet Adm Hosp, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Wang, ZM ] S
[Hu, R ] U
Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
South China Univ Technol, AIE Inst, Ctr Aggregat Induced Emiss, State Key Lab Luminescent Materials & Devices,Guan, Guangzhou 510640, Peoples R China.
语种:
英文
关键词:
Aggregation-induced emission;Detection;Discrimination;Keto-salicylaldehyde azine;Microorganism;Structure-property relationship
期刊:
Biosensors and Bioelectronics
ISSN:
0956-5663
年:
2025
卷:
271
页码:
116952
基金类别:
National Natural Science Foundation of China [21975077]; Fund of University of South China [211RGC011]; Natural Science Foundation of Guangdong Province [2022B1515020084]; Open Fund of Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, Guangzhou, China (South China University of Technology) [2023B1212060003]
机构署名:
本校为第一且通讯机构
院系归属:
化学化工学院
摘要:
The rapid and selective identification of microorganisms is of great significance for clinical therapy applications. To develop high performance probes for microbe determination, we systemically constructed series aggregation-induced emission (AIE) luminogens by modulating the structural planarity, the basicity of functional group, the length of linker moiety and the hydrophobicity based on our previous work. The detail structure-property relationship study based on experimental and theoretical observation revealed that: i) the planar skeleton is essential for probe insertion towards the cell ...

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