Microplastics and Skin Aging: Disruption of Barrier Function and Induction of Fibroblast Senescence

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Ouyang, Yujie;Wu, Songjiang;Zhao, Yuanyuan;Hu, Yibo;Jiang, Ling;...

通讯作者：

Chen, Jing;Zeng, QH

作者机构：

[Huang, Jinhua; Zeng, Qinghai; Zeng, QH; Zhang, Yushan; Duan, Xiaolei; Zhao, Yuanyuan; Jiang, Ling; Lei, Li; Fu, Chuhan; Chen, Jing; Ouyang, Yujie] Cent South Univ, Xiangya Hosp 3, Dept Dermatol, Changsha, Hunan, Peoples R China.

[Wu, Songjiang] Univ South China, Affiliated Hosp 1, Hengyang Med Coll, Dept Dermatol, Hengyang, Hunan, Peoples R China.

[Hu, Yibo] Cent South Univ, Xiangya Hosp 2, Clin Res Ctr, Changsha, Hunan, Peoples R China.

[Hu, Yibo] Cent South Univ, Xiangya Hosp 2, Dept Dermatol, Changsha, Hunan, Peoples R China.

通讯机构：

[Chen, J; Zeng, QH ] C

Cent South Univ, Xiangya Hosp 3, Dept Dermatol, Changsha, Hunan, Peoples R China.

语种：

英文

关键词：

extracellular matrix;microplastics;polystyrene;PPAR gamma;skin barrier

期刊：

Experimental Dermatology

ISSN：

0906-6705

年：

2025

卷：

期：

页码：

e70027-

DOI：

10.1111/exd.70027

基金类别：

This research was supported by the National Natural Science Foundation of China (No. 82073421), Natural Science Foundation of Hunan Province (No. 2022JJ30880 and No. 2024JJ5360), Scientific Research Program of Hunan Provincial Health Commission (No. 20240304082) and Young Elite Scientists Sponsorship Program by CACM (No. CACM-2023-QNRC2-B30). Yujie Ouyang and Songjiang Wu contributed equally.

机构署名：

本校为其他机构

摘要：

ABSTRACT Microplastics (MPs) have emerged as a major concern among contemporary pollutants, but there is still limited knowledge regarding their impact on skin function. To address this issue, we conducted a transcriptome analysis on skin tissue that had been exposed to polystyrene (PS), which is one of the most prevalent type of MPs that can be absorbed through the skin. The results of our study, obtained through functional enrichment analysis and the experiment of treating HaCaT with PS, revealed that PS may have an effect on skin barrier fun...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Microplastics and Skin Aging: Disruption of Barrier Function and Induction of Fibroblast Senescence

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问