Currently, the methods to ensure the safety of radioactive materials include intrusion alarm system, video surveillance system and access control system. However, radioactive substances may lose their security protection when faced with non-traditional security threats such as low-altitude or underwater threats, or sys-tem failure, which may lead to incidents of loss or being stolen of the radioactive substances. This paper dis-cusses the concept of self-security intelligence of individual radioactive substances which endows them with the ability to perceive and respond to danger. A novel secu...