The radiation safety regulatory agencies and legislation were introduced preliminarily in this paper based on Peru ^192Ir Source Industrial Radiography Radiation Accident in 2012(PISIRRA). And the accident process, emergency response, preliminary dose assessment, clinical manifestations and diagnoses, International Atomic Energy Agency (IAEA) assistance medical recommendations, dose reconstruction, medical management of the exposed patients, conclusions and lessons learned for PISIRRA were analyzed and explained at the same time. The practice of PISIRRA proved that the the main cause of the ac...