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The Relationship Between Hepcidin-Mediated Iron Dysmetabolism and COVID-19 Severity: A Meta-Analysis

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成果类型:
期刊论文
作者:
Peng, Denggao;Gao, Yanzhang;Zhang, Li;Liu, Zhichao;Wang, Huan;...
通讯作者:
Liu, Y.
作者机构:
[Gao, Yanzhang; Liu, Zhichao; Wang, Huan; Liu, Yingxia; Zhang, Li; Peng, Denggao] Southern Univ Sci & Technol, Shenzhen Peoples Hosp 3, Hosp 2, Shenzhen, Peoples R China.
[Liu, Yingxia; Peng, Denggao] Univ South China, Grad Collaborat Training Base Shenzhen Peoples Hos, Hengyang Med Sch, Hengyang, Peoples R China.
通讯机构:
[Liu, Y.] S
Shenzhen Third People's Hospital, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen, China
语种:
英文
关键词:
COVID-19;ferritin;hepcidin;iron metabolism;severity
期刊:
Frontiers in Public Health
ISSN:
2296-2565
年:
2022
卷:
10
页码:
881412
基金类别:
The authors thank Professor Hai Rao, School of Medicine, Southern University of Science and Technology, China, and Cindy Acon Chen, USA, for reviewing this manuscript.
机构署名:
本校为其他机构
摘要:
Backgrounds: Hepcidin has been identified as a systemic iron-regulatory hormone. Recent studies have suggested that iron metabolism disorders may be involved in the pathogenesis of acute respiratory distress syndrome and multiple organ dysfunction in coronavirus disease 2019 (COVID-19). Objectives: To re-evaluate the hepcidin-related iron metabolism parameters and explore the relationship between hepcidin-mediated iron dysmetabolism and COVID-19 severity. Methods: COVID-19 is classified as mild and moderate as non-severe, severe and critical as...

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