期刊论文

英文

Frontiers in Psychiatry

1664-0640

2022

13

830541

10.3389/fpsyt.2022.830541

This study was supported by Key Science and Technology Project of Hainan Province (ZDYF2021SHFZ239), the National Nature Science Foundation of China (Grant Nos. 81971602 and 81760308 for FC, Grant No. 81871346 for WH, and Grant No. 82160327 for TL), the Hainan Academician Innovation Platform Fund, and the Hainan Province Clinical Medical Center, Natural Science Research Project of Hainan Medical University (JBGS202107).

本校为第一机构

ObjectiveThis study aimed to investigate brain spontaneous neural activity changes in betel quid dependence (BQD) chewers using the percent amplitude of fluctuation (PerAF) method. MethodsThis study included 48 BQD chewers. The healthy control (HC) group comprised 35 volunteers who were matched with BQD chewers in age, gender, and educational status. All subjects underwent resting-state functional magnetic resonance imaging (rs-fMRI) and neuropsychological tests. The PerAF method was used to identify BQD-related regional brain activity changes. An independent samples t-test was used to evaluat...