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Microcystins Exposure Associated with Blood Lipid Profiles and Dyslipidemia: A Cross-Sectional Study in Hunan Province, China

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成果类型:
期刊论文
作者:
Feng, Shuidong;Cao, Mengyue;Tang, Peng;Deng, Shuxiang;Chen, Limou;...
通讯作者:
Minxue Shen<&wdkj&>Fei Yang
作者机构:
[Tang, Peng; Deng, Shuxiang; Chen, Limou; Feng, Shuidong; Cao, Mengyue; Yang, Fei; Tang, Yan] Univ South China, Sch Basic Med, Sch Publ Hlth, Hengyang Med Sch,Dept Epidemiol & Hlth Stat,Key La, Hengyang 421001, Peoples R China.
[Zhu, Lemei] Changsha Med Univ, Sch Publ Hlth, Changsha 410219, Peoples R China.
[Chen, Xiang] Cent South Univ, Xiangya Hosp, Hunan Engn Res Ctr Skin Hlth & Dis, Xiangya Clin Res Ctr Canc Immunotherapy,Dept Derma, Changsha 410008, Peoples R China.
[Shen, Minxue; Huang, Zhijun; Chen, Xiang] Furong Lab, Changsha 410008, Peoples R China.
[Huang, Zhijun] Cent South Univ, Xiangya Hosp 3, Ctr Clin Pharmacol, Changsha 410013, Peoples R China.
通讯机构:
[Minxue Shen; Fei Yang] A
Authors to whom correspondence should be addressed.<&wdkj&>Hunan Provincial Key Laboratory of Clinical Epidemiology, Xiangya School of Public Health, Department of Social Medicine and Health Management, Central South University, Changsha 410000, China<&wdkj&>Furong Laboratory, Changsha 410008, China<&wdkj&>Authors to whom correspondence should be addressed.<&wdkj&>Hunan Provincial Key Laboratory of Clinical Epidemiology, Xiangya School of Public Health, Department of Social Medicine and Health Management, Central South University, Changsha 410000, China<&wdkj&>Department of Epidemiology and Health Statistics, The Key Laboratory of Typical Environmental Pollution and Health Hazards of Hunan Province, School of Basic Medicine, School of Public Health, Hengyang Medical School, University of South China, Hengyang 421001, China
语种:
英文
关键词:
microcystins;triglyceride;cholesterol;lipoprotein;lipid profiles;dyslipidemia;cross-sectional study
期刊:
TOXINS
ISSN:
2072-6651
年:
2023
卷:
15
期:
4
页码:
293-
基金类别:
Conceptualization, S.F., M.C., Y.T. and F.Y.; Methodology, S.F., M.C., P.T., S.D., L.C., L.Z., Z.H., M.S. and F.Y.; Formal analysis, S.F. and M.C.; Investigation, L.C.; Resources, X.C. and F.Y.; Data curation, Y.T., M.S. and F.Y.; Writing—original draft, S.F. and M.C.; Writing—review and editing, M.C., P.T., S.D., M.S. and F.Y.; Visualization, S.F., M.C. and S.D.; Supervision, M.S. and F.Y.; Project administration, F.Y.; Funding acquisition, M.S. and F.Y. All authors have read and agreed to the published version of the manuscript. This research was funded by the Huxiang Youth Talent Program (2021RC3107, 2022RC1014), the Key Research and Development Projects in Hunan Province (2022SK2089), and the Project of Intelligent Management Software for Multimodal Medical Big Data for New Generation Information Technology, Ministry of Industry and Information Technology of People’s Republic of China (TC210804V).
机构署名:
本校为第一机构
院系归属:
公共卫生学院
摘要:
Increasing evidence from experimental research suggests that exposure to microcystins (MCs) may induce lipid metabolism disorder. However, population-based epidemiological studies of the association between MCs exposure and the risk of dyslipidemia are lacking. Therefore, we conducted a population-based cross-sectional study involving 720 participants in Hunan Province, China, and evaluated the effects of MCs on blood lipids. After adjusting the lipid related metals, we used binary logistic regression and multiple linear regression models to ex...

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