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Irradiation increases brain-derived neurotrophic factor precursor signaling in the mouse hippocampus

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成果类型:
期刊论文
作者:
Wang, Zhen;Zhong, Xiao Lin;Xu, Yang;He, Jie;Liu, Zheng Hai;...
通讯作者:
Wan, Wei;Cao, Wen Yu
作者机构:
[Chen, Xi; Liu, Zheng Hai; Wang, Zhen; Zeng, Jia Yu; Cao, Wen Yu; Niu, Lei; Wan, Wei; Luo, Shi Shi; Cao, WY] Univ South China, Sch Med, Clin Anat & Reprod Med Applicat Inst, Hengyang 421001, Hunan, Peoples R China.
[Zhong, Xiao Lin] Univ South China, Inst Clin Med, Affiliated Hosp 1, Hengyang 421001, Hunan, Peoples R China.
[Xu, Yang] Univ South China, Med Coll, Inst Neurosci, Hengyang 421001, Hunan, Peoples R China.
[He, Jie; Yang, Hui] Univ South China, Med Coll, Dept Pathol, Hengyang 421001, Hunan, Peoples R China.
[Nai, Ai Tao] Univ South China, Dept Radiat Oncol, Affiliated Hosp 1, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Wan, W; Cao, WY] U
Univ South China, Sch Med, Clin Anat & Reprod Med Applicat Inst, Hengyang 421001, Hunan, Peoples R China.
语种:
英文
关键词:
brain derived neurotrophic factor;brain derived neurotrophic factor;brain-derived neurotrophic factor precursor;membrane protein;Ntrk2 protein, mouse;protein precursor;protein tyrosine kinase;adult;animal experiment;animal tissue;Article;BDNF signaling;controlled study;enzyme inhibition;experimental cognitive test;female;hippocampus;immunohistochemistry;irradiation;mouse;neuroapoptosis;nonhuman;novel object recognition test;novel place recognition test;open field test;protein expression;protein processing;real time polymerase chain reaction;RNA isolation;signal transduction;Western blotting;animal;hippocampus;metabolism;physiology;radiation response;signal transduction;whole body radiation;Animals;Brain-Derived Neurotrophic Factor;Female;Hippocampus;Membrane Glycoproteins;Mice;Protein Precursors;Protein-Tyrosine Kinases;Recognition, Psychology;Signal Transduction;Whole-Body Irradiation
期刊:
Neurobiology of Learning and Memory
ISSN:
1074-7427
年:
2020
卷:
171
页码:
107186
基金类别:
This work was supported by the National Natural Science Foundation of China ( 31701045 ), the Hunan Provincial Natural Science Foundation of China ( 2018JJ3429 , 2018JJ3460 , 2018JJ4034 ) and the Hunan Provincial Education Department Foundation of China ( 16A187 , 14A125 , 17B230 ). The authors would like to acknowledge Dr. Shu Ya, He for her assistance with these experiments.
机构署名:
本校为第一且通讯机构
院系归属:
医学院
公共卫生学院
摘要:
H...
摘要(中文):
[无可用...

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