Inhibited Endogenous H2S Generation and Excessive Autophagy in Hippocampus Contribute to Sleep Deprivation-Induced Cognitive Impairment

首页 > 成果 > 详情

认领

导出

下载 Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Yang, San-Qiao;Jiang, Li;Lan, Fang;Wei, Hai-jun;Xie, Ming;...

通讯作者：

Tang, Xiao-Qing;Zou, Wei

作者机构：

[Wei, Hai-jun; Yang, San-Qiao; Wang, Chun-Yan; Tang, Xiao-Qing; Jiang, Li; Lan, Fang] Univ South China, Hengyang Med Coll, Inst Neurosci, Hengyang, Peoples R China.

[Zou, Wei; Jiang, Li; Zhang, Ping] Univ South China, Affiliated Nanhua Hosp, Dept Neurol, Hengyang, Peoples R China.

[Tang, Xiao-Qing; Lan, Fang; Xie, Ming] Univ South China, Affiliated Hosp 1, Dept Neurol, Hengyang, Peoples R China.

[Xie, Yu-Rong] Univ South China, Coll Chem & Chem Engn, Hengyang, Peoples R China.

通讯机构：

[Tang, Xiao-Qing; Zou, Wei] U

Univ South China, Hengyang Med Coll, Inst Neurosci, Hengyang, Peoples R China.

Univ South China, Affiliated Nanhua Hosp, Dept Neurol, Hengyang, Peoples R China.

Univ South China, Affiliated Hosp 1, Dept Neurol, Hengyang, Peoples R China.

语种：

英文

关键词：

autophagy;cognitive impairment;hippocampus;hydrogen sulfide;sleep deprivation

期刊：

FRONTIERS IN PSYCHOLOGY

ISSN：

1664-1078

年：

2019

卷：

期：

JAN

页码：

DOI：

10.3389/fpsyg.2019.00053

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81671057, 81771178]; Major Research Topics of the Health and Family Planning Commission of Hunan Province [A2017020]; Key Projects of the Education Department of Hunan Province [17A187]

机构署名：

本校为第一且通讯机构

院系归属：

化学化工学院

医学院

摘要：

Background and Aim: Sleep deprivation (SD) causes deficit of cognition, but the mechanisms remain to be fully established. Hydrogen sulfide (H2S) plays an important role in the formation of cognition, while excessive and prolonged autophagy in hippocampus triggers cognitive disorder. In this work, we proposed that disturbances in hippocampal endogenous H2S generation and autophagy might be involved in SD-induced cognitive impairment. Methods: After treatment of adult male wistar rats with 72-h SD, the Y-maze test, object location test (OLT), novel object recognition test (NORT) and the Morris ...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Inhibited Endogenous H2S Generation and Excessive Autophagy in Hippocampus Contribute to Sleep Deprivation-Induced Cognitive Impairment

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问