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Research and progress of inflammasomes in nonalcoholic fatty liver disease

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成果类型:
期刊论文
作者:
Chen, Ke-qian;Ke, Bo-yi;Cheng, Lu;Yu, Xiao-qing;Wang, Zong-bao;...
通讯作者:
Shu-zhi Wang
作者机构:
[Wang, Shu-zhi] Univ South China, Inst Pharm & Pharmacol, Sch Pharmaceut Sci, Hengyang Med Sch, Hengyang 421001, Peoples R China.
Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dru, Hengyang 421001, Peoples R China.
通讯机构:
[Wang, S.-Z.] I
Institute of Pharmacy and Pharmacology, China
语种:
英文
关键词:
Fibrosis;Liver inflammation;NLRP3;Nonalcoholic fatty liver disease;Nonalcoholic steatohepatitis;Steatosis
期刊:
International Immunopharmacology
ISSN:
1567-5769
年:
2023
卷:
118
页码:
110013
基金类别:
This work was supported by Scientific Research Project of Hunan Provincial Department of Education (20 K106) and Project of Hunan Provincial Health Committee (D202302048902).
机构署名:
本校为第一机构
院系归属:
药学与生物科学学院
摘要:
With the development of the social economy, unhealthy living habits and eating styles are gradually affecting people's health in recent years. As a chronic liver disease, NAFLD is deeply affected by unhealthy living habits and eating styles and has gradually become an increasingly serious public health problem. As a protein complex in clinical research, the inflammasomes play a crucial role in the development of NAFLD, atherosclerosis, and other diseases. This paper reviews the types, composition, characteristics of inflammasomes, and molecular mechanism of the inflammasome in NAFLD. Meanwhile...

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