期刊论文

中文

吉林医学

1004-0412

2012

33

16

3367-3368

10.3969/j.issn.1004-0412.2012.16.002

本校为第一机构

目的:检测冠脉严重狭窄的冠心病患者的血清ICAM-1浓度,探讨ICAM-1 浓度与冠脉侧支循环形成与否的相关性.方法:通过冠脉造影检查,收集主要冠脉至少一支狭窄程度在95%以上的108例冠心病患者,测定其血清ICAM-1浓度.采用Rentrop方法对冠脉侧支循环进行分级,0级为侧支循环未形成组(n=47),1～3级为侧支循环形成组(n=61).结果:与侧支循环形成组(243.08±70.90 ng/ml)相比,侧支循环未形成组血清ICAM-1浓度(286.38±56.27 ng/ml)明显增高,差异有统计学意义(P=0.001,P＜0.01).结论:冠脉严重狭窄的冠心病患者血清ICAM-1浓度与冠脉侧支循环形成呈负相关.

Objective To investigate the relationship between the levels of serum intercellular adhesion molecules - 1 （ ICAM - 1 ） and the formation of coronary collateral circulation in patients with severe coronary artery stenosis. Method Total 108 patients with at least the stenosis of one vessel ≥95% among three main vessels of coronary artery were consecutively enrolled in the study according to anglographic estimation. Development of collaterals was classified by Rentrop＇s method. According to the collateral degree,patients were divided into two...