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Simultaneous fluorescence analysis of the different carbohydrates expressed on living cell surfaces using functionalized quantum dots

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成果类型:
期刊论文
作者:
He, Dongxiu*;Wang, Danxia;Shi, Xiaoxin;Quan, Wenjie;Xiong, Runde;...
通讯作者:
He, Dongxiu
作者机构:
[Huang, Honglin; Yua, Cui-yun; He, Dongxiu; Wang, Danxia] Univ South China, Inst Pharm & Pharmacol, Hengyang, Hunan, Peoples R China.
[Quan, Wenjie; Shi, Xiaoxin; Yua, Cui-yun; He, Dongxiu; Xiong, Runde] Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang, Hunan, Peoples R China.
通讯机构:
[He, Dongxiu] U
[He, Dongxiu] H
Univ South China, Inst Pharm & Pharmacol, Hengyang, Hunan, Peoples R China.
Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang, Hunan, Peoples R China.
语种:
英文
期刊:
RSC Advances
ISSN:
2046-2069
年:
2017
卷:
7
期:
20
页码:
12374-12381
基金类别:
National Natural Science Foundation of China [81471777]; Administration of Traditional Chinese Medicine of Hunan Province [201412]; Natural Science Foundation of Hunan province [16JJ66126]
机构署名:
本校为第一且通讯机构
院系归属:
药学与生物科学学院
摘要:
The aberrant expression of carbohydrates has been associated with the occurrence, growth, progression and metastasis of tumors. Tumor-associated carbohydrates may have great potential as tumor markers for the early diagnosis of hepatocellular carcinoma (HCC). Therefore, characterizing HCC-associated carbohydrate expression is of great importance to assist the early diagnosis of HCC. A fluorescence method for characterizing carbohydrates expressed on both normal human cells (LO2 cells and endothelial cells) and HCC cells (HepG2 cells) using func...

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