We have prepared a nanoparticle-based metronidazole-imprinted polymer by combining a surface molecular imprinting technique with a sol-gel process. Metronidazole was used as a template, 3-aminoprophyltriethoxysilane as the functional monomer, and tetraethyl orthosilicate as the cross-linker. The resulting magnetic molecularly imprinted polymer was characterized by Fourier transform infrared spectroscopy, powder X-ray diffraction and scanning electron microscopy. The adsorbent can be applied to the solid phase extraction of metronidazole and exh...