Dendrobium nobile-derived polysaccharides ameliorate spermatogenic disorders in mice with streptozotocin-induced diabetes through regulation of the glycolytic pathway

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Luo, Min;Liao, Biyun;Ma, Duo;Wang, Jinyuan;Wang, Junli;...

通讯作者：

Long, Shuanglian;Yang, Fenglian;Lei, Xiaocan

作者机构：

[Luo, Min; Cai, Yongqin; Tang, Lixin; Lei, Xin; Wang, Jinyuan; Liu, Jiang; Lei, Xiaocan; Ma, Duo; Zhao, Leilei; Long, Shuanglian] Univ South China, Clin Anat & Reprod Med Applicat Inst, Hengyang Med Sch, Dept Histol & Embryol, Hengyang 421001, Peoples R China.

[Wang, Junli; Liao, Biyun] Youjiang Med Univ Nationalities, Reprod Med Ctr, Affiliated Hosp, Baise 533000, Peoples R China.

[Yang, Fenglian] Youjiang Med Univ Nationalities, Key Lab Environm Pollut & Hlth Risk Assessment, Baise 533000, Peoples R China.

通讯机构：

[Long, Shuanglian; Lei, Xiaocan] C

[Yang, Fenglian] K

Clinical Anatomy and Reproductive Medicine Application Institute, Department of Histology and Embryology, Hengyang Medical School, University of South China, Hengyang 421001, China. Electronic address:

Key Laboratory of Environmental Pollution and Health Risk Assessment, Youjiang Medical University for Nationalities, Baise 533000, China. Electronic address:

语种：

英文

关键词：

Apoptosis;Dendrobium nobile polysaccharide;Diabetes mellitus;Glycolysis;Spermatogenesis

期刊：

International Journal of Biological Macromolecules

ISSN：

0141-8130

年：

2022

卷：

216

页码：

203-212

DOI：

10.1016/j.ijbiomac.2022.06.193

基金类别：

National Natural Science Foundation of China [81860733]; Foundation of the Central Government to Guide Local Scientific and Technological Development [ZY21195023]; Science and Technology Fund of Hunan Province [2020JJ5500, 2020JJ4531]; Scientific Research Elevation Project of Young Faculty from Guangxi Universities [2019KY0567]; Scientific Research and Technological of Baise in China [20183331]; Hunan Province Innovation and Entrepreneurship Training Program for College Students [X202110555526, X2020105555391]

机构署名：

本校为第一机构

院系归属：

医学院

摘要：

Dysfunction of spermatogenesis is a major complication of diabetes mellitus (DM). This study characterized the protective effects of Dendrobium nobile-derived polysaccharides (DNP) against spermatogenetic dysfunction in mice with streptozotocin (STZ)-induced diabetes. The diabetic mice had lower body and testicular mass, and fewer spermatozoa with a higher incidence of malformation. The testicular histology showed disordered narrow seminiferous tubules covering a smaller area, and fewer spermatogenic cells. Moreover, the qRT-PCR analysis indicated that DM was associated with high expression of...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Dendrobium nobile-derived polysaccharides ameliorate spermatogenic disorders in mice with streptozotocin-induced diabetes through regulation of the glycolytic pathway

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问