circ0125803 facilitates tumor progression by sponging miR-197–5p and upregulating E2F1 in neuroblastoma

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Tang, Jue;Liu, Feng;Huang, Dongmei;Zhao, Congling;Liang, Jianghua;...

通讯作者：

Li, L;Zhai, XH

作者机构：

[Huang, Dongmei; Tang, Jue; Li, Le; Wang, Fenghua; Liang, Jianghua; Zeng, Jiahang] Guangzhou Med Univ, Guangzhou Inst Pediat, Guangzhou Women & Childrens Med Ctr, Dept Pediat Surg, Guangzhou 510623, Guangdong, Peoples R China.

[Zhang, Meilan; Liu, Feng] Univ South China, Hengyang Med Sch, Canc Res Inst, Hengyang, Peoples R China.

[Zhao, Congling] Guangdong Women & Children Hosp, Dept Pediat, Guangzhou, Guangdong, Peoples R China.

[Zhai, Xiaohui; Zhai, XH] Sun Yat Sen Univ, Dept Med Oncol, Affiliated Hosp 6, Guangzhou, Guangdong, Peoples R China.

通讯机构：

[Zhai, XH ] S

[Li, L ] G

Guangzhou Med Univ, Guangzhou Inst Pediat, Guangzhou Women & Childrens Med Ctr, Dept Pediat Surg, Guangzhou 510623, Guangdong, Peoples R China.

Sun Yat Sen Univ, Dept Med Oncol, Affiliated Hosp 6, Guangzhou, Guangdong, Peoples R China.

语种：

英文

关键词：

Circ0125803;CircRNA;Competitive endogenous RNAs;E2F1;Neuroblastoma

期刊：

PATHOLOGY RESEARCH AND PRACTICE

ISSN：

0344-0338

年：

2022

卷：

233

页码：

153857

DOI：

10.1016/j.prp.2022.153857

基金类别：

This study was supported by grants from the Science and Technology Projects of Guangzhou Health Committee (No: 20191A011030).

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

BACKGROUND: Circular RNAs (circRNAs) are one type of RNAs with many different functions. circRNAs are very crucial in human malignancy progression. However, few studies have investigated the function and exact mechanism of circRNAs in neuroblastoma. In the current study, we investigated the biological function of circ0125803 in the proliferation and metastasis of neuroblastoma. METHODS: A high-throughput circRNA microarray sequencing was conducted to screen differentially expressed circRNAs and in neuroblastoma. Quantitative real-time polymerase chain reaction (qRT-PCR) was used to detect the ...

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circ0125803 facilitates tumor progression by sponging miR-197–5p and upregulating E2F1 in neuroblastoma

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