期刊论文

Research progress of miRNA on mitochondrial function

中文

生命的化学

1000-1336

2020

40

02

250-255

10.13488/j.smhx.20190197

国家自然科学基金项目（31670962）；

本校为第一机构

MiRNA为小分子非编码RNA,通过与靶基因的相互作用调节靶基因的表达,参与调控细胞的多个生物学过程。本文综述了miRNA与线粒体生物合成、线粒体动力学、线粒体能量代谢、线粒体钙稳态、线粒体自噬间的关系及其调节机制,阐述了microRNA调节线粒体功能的研究进展。

Mi RNA is a small molecule non-coding RNA that regulates the expression of target genes by interacting with target genes and participates in the regulation of multiple biological processes in cells. This review summarized the relationship of miRNAs with mitochondrial biosynthesis, mitochondrial dynamics, mitochondrial energy metabolism, mitochondrial calcium homeostasis, mitophagy and the regulatory mechanisms.We also reviewed the researc...