Protein kinase C (PKC) isozymes are a family of serine/threonine kinases, and form AGC family together with protein kinase A and protein kinase G. PKC isozymes are ubiquitously expressed in all tissues at all times of development. PKCs are now known to be major mediators of signal transduction pathways and have been shown to regulate sets of biological functions as diverse as cell growth, differentiation, apoptosis, transformation, tumourigenicity, and so on. Many diseases are associated with PKCs such as diabetes, heart failure, neurodegenerative diseases, tumors, and so on. This review descr...
