Midkine is a secreted heparin-binding growth factor, which plays an important role in inflammation, tumor, metabolism diseases and early development of embryos. Atherosclerosis is a kind of common cardiovascular diseases and the specific pathogenesis has not been fully elucidated so far. Studies have shown that atherosclerosis is a chronic inflammation disease of the damaged vessel, and in close relation with heredity, environment and lipid metabolism. Midkine plays an important role in lipid metabolism, oxidative stress and inflammation, and is closely related to atherosclerosis. This article...
