Mitochondria are the power house of the cell, which is a highly dynamic double-membrane-bound organelle that is widely distributed in many cell types. Many studies have shown that mitochondria not only play a key role in maintaining cellular energy homeostasis, but also participate in the regulation of calcium signal transduction, cell proliferation and differentiation. Recent studies have shown that mitochondrial injury is involved in the initiation and progression of atherosclerosis. In this review, we have analyzed the recent ad- vances in mitochondrial injury and atherosclerosis, in order ...