Atherosclerosis is a result of a combination of lipid metabolism disorders and inflammation. Cell death can be observed in atherosclerosis and play an important role in the development and progression of atherosclerotic lesions. Inflammation is the primary response to innate immunity and is thought to be necessary to initiate and drive atherosclerosis. Apoptosis, autophagy and necrosis have been reported in atherosclerosis. However, the mechanisms of cell death involved in atherosclerosis are still largely unknown. Pyroptosis is a newly discovered method of programmed cell death, which partici...
