Angiopoietin-like protein 3(ANGPTL3) is a secretory glycoprotein, it has closely relationship with metabolic disorders diseases, like familial combined hypobetalipoproteinemia, atherosclerosis and type 2 diabetes mellitus. It is known that ANGPTL3 palys an important role in the metabolism of lipids and angiogenesis progress. The entire understanding of ANGPTL3 intimate mechanism of action might be able ...