Abstract： As a transcription auxiliary inhibitor, receptor-interacting protein 140 （RIP140） is involved in the regulation of metabolism in human body. Once combined with nuclear receptor, RIP140 can negatively regulate the transcription of target genes within a variety of metabolic organizations include the adipose tissue, muscle tissue, cardiac muscle and liver. When silenced, on the contrary, RIP140 will have an influence on glycolysis, triglyceride metabolism, the tricarboxylic acid cycle, fatty acid 13 oxidation, inflammatory factor expr...
