Exosome-based nanomedicines for digestive system tumors therapy

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Song, Ge;Zeng, Chenlu;Li, Junru;Liu, Jiajia;Zhao, Juanxia;...

通讯作者：

Xie, HL;Fan, JL

作者机构：

[Zeng, Chenlu; Xie, Hailong; Li, Junru; Song, Ge; Liu, Jiajia; Xie, HL] Univ South China, Canc Res Inst Hengyang Med Coll, Key Lab Canc Cellular & Mol Pathol Hunan Prov, Hengyang 421001, Hunan, Peoples R China.

[Zhao, Juanxia] Univ South China, Affiliated Nanhua Hosp, Hengyang Med Coll, Dept Pathol, Hengyang, Hunan, Peoples R China.

[Liu, Bin] Hunan Univ, Coll Biol, Changsha, Hunan, Peoples R China.

[Fan, Jialong; Fan, JL] Changsha Med Univ, Hunan Prov Key Lab Res & Dev Novel Pharmaceut Prep, Changsha 410219, Peoples R China.

通讯机构：

[Fan, JL ] C

[Xie, HL ] U

Univ South China, Canc Res Inst Hengyang Med Coll, Key Lab Canc Cellular & Mol Pathol Hunan Prov, Hengyang 421001, Hunan, Peoples R China.

Changsha Med Univ, Hunan Prov Key Lab Res & Dev Novel Pharmaceut Prep, Changsha 410219, Peoples R China.

语种：

英文

关键词：

Exosomes;digestive system tumors;drug delivery;tumor therapy;exosome source

期刊：

NANOMEDICINE

ISSN：

1743-5889

年：

2025

卷：

期：

页码：

1167-1180

DOI：

10.1080/17435889.2025.2493037

基金类别：

Natural Science Foundation of Hunan Province [2024JJ9400]; Natural Science Foundation of Hunan Province [D202405241005372877]; Student Innovation and Entrepreneurship Training Program of Hunan Province [24B0889]; Science Project of the Education Department of Hunan Province

机构署名：

本校为第一且通讯机构

院系归属：

医学院

摘要：

Digestive system tumors constitute a major subset of malignancies, consistently ranking among the leading causes of mortality globally. Despite limitations inherent in current therapeutic modalities, recent advancements in targeted therapy and drug delivery systems have led to significant improvements in the efficacy of pharmacotherapy for digestive system tumors. In this context, exosomes - naturally occurring nanoscale vesicles - have emerged as promising drug delivery candidates due to their intrinsic molecular transport capabilities, superior biocompatibility, and targeted recognition of t...

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